Around 7000 BCE, the Pre-Harappan Civilisation, also called Mehrgarh (Say Mehurgudh- no mistake in the spellings), the 2nd earliest known civilisation, started and it lasted until c. 3300 BCE, when the Early Harappan Period appeared and continued to flourish until the end of the Mature Harappan Period (2600 - 1900 BCE).
And by 'flourish', I mean that they had very advanced systems of hygiene. They had sewer systems, and the cities were very carefully planned. Also, their bricks were in a ratio, and they had a citadel in the center of towns to keep shelter. To add on even more, one of the most fascinating things in history is the fact that the harappans had bricks that were in ratio. This means that if a brick were Size 1, the next would be Size 1.5, then 2, etc.
At 2800 BCE, they were fragmented and were a fairly small civilisation, but around 2000 BCE, as I said, they reached their height.
From 1900-1700 BCE (The Late Period), there was an increase in violence and diseases that weakened the civilisation, and by 1300 BCE it hardly existed any more.
Another notable civilisation nearby (Some say that it was part of the Harappan Civilisation) was the Bara Civilisation, between the Yamuna and Sutlej Rivers, located in Northern India. Recent studies show that the architecture was different, and that it was another civilisation.